Paralogue Annotation for KCNH2 residue 205

Residue details

Gene: KCNH2
Reference Sequences: LRG: LRG_288, Ensembl variant: ENST00000262186 / ENSP00000262186
Amino Acid Position: 205
Reference Amino Acid: P - Proline
Protein Domain: N-terminus


Paralogue Variants mapped to KCNH2 residue 205

No paralogue variants have been mapped to residue 205 for KCNH2.



KCNH2ARESSVRSGGAGGAGAPGAVVVDVDLTPAA>P<SSESLALDEVTAMDNHVAGLGPAEERRALV235
KCNH1------------------------------>-<------------------------------
KCNH3------------------------------>-<------------------------------
KCNH4------------------------------>-<------------------------------
KCNH5------------------------------>-<------------------------------
KCNH6SEGSHGRPGGPG------------------>-<---------------------PG-------169
KCNH7YRKQSLPQEDPD------VVVIDS----SK>H<SDDSVAMKHFKSPTKESCSPSEADDTKALI220
KCNH8------------------------------>-<------------------------------
CNGA1------------------------------>-<------------------------------
CNGA2------------------------------>-<------------------------------
CNGA3------------------------------>-<------------------------------
CNGA4------------------------------>-<------------------------------
CNGB1AKKEAEEKAKEEAEEVAEEEAEKEPQDWAE>T<KEEPEAEAEAASSGVPATKQHPEVQVEDTD473
CNGB3ENKGEEKSLKTKSTPVTSEEPHTNIQDKLS>K<KN---------SSGDLTTNPDPQNAAEPTG96
HCN1------------------------------>-<------------------------------
HCN2------------------------------>-<------------------------------
HCN3------------------------------>-<------------------------------
HCN4------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNH2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.P205Tc.613C>A Putative BenignSIFT: tolerated
Polyphen: benign