Paralogue Annotation for KCNH2 residue 214

Residue details

Gene: KCNH2
Reference Sequences: LRG: LRG_288, Ensembl variant: ENST00000262186 / ENSP00000262186
Amino Acid Position: 214
Reference Amino Acid: E - Glutamate
Protein Domain: N-terminus


Paralogue Variants mapped to KCNH2 residue 214

No paralogue variants have been mapped to residue 214 for KCNH2.



KCNH2GAGGAGAPGAVVVDVDLTPAAPSSESLALD>E<VTAMDNHVAGLGPAEERRALVGPGS-----239
KCNH1------------------------------>-<------------------------------
KCNH3------------------------------>-<------------------------------
KCNH4------------------------------>-<------------------------------
KCNH5------------------------------>-<------------------------------
KCNH6GPG--------------------------->-<------------PG----------------169
KCNH7DPD------VVVIDS----SKHSDDSVAMK>H<FKSPTKESCSPSEADDTKALIQPSK-----224
KCNH8------------------------------>-<------------------------------
CNGA1------------------------------>-<------------------------------
CNGA2------------------------------>-<------------------------------
CNGA3------------------------------>-<------------------------------
CNGA4------------------------------>-<------------------------------
CNGB1KEEAEEVAEEEAEKEPQDWAETKEEPEAEA>E<AASSGVPATKQHPEVQVEDTDADSCPLMAE482
CNGB3KTKSTPVTSEEPHTNIQDKLSKKN------>-<--SSGDLTTNPDPQNAAEPTGT--------97
HCN1------------------------------>-<------------------------------
HCN2------------------------------>-<------------------------------
HCN3------------------------------>-<------------------------------
HCN4------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNH2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.E214Kc.640G>A Putative BenignSIFT:
Polyphen: