Paralogue Annotation for KCNH2 residue 271

Residue details

Gene: KCNH2
Reference Sequences: LRG: LRG_288, Ensembl variant: ENST00000262186 / ENSP00000262186
Amino Acid Position: 271
Reference Amino Acid: R - Arginine
Protein Domain: N-terminus


Paralogue Variants mapped to KCNH2 residue 271

No paralogue variants have been mapped to residue 271 for KCNH2.



KCNH2PRAHSLNPDASGSS------CSL----ART>R<SRESCASVRRASSADDIEAM--------RA293
KCNH1------------------------------>-<------------------------------
KCNH3---------------------RY----GRA>R<------------------------------159
KCNH4---------------------SL----GRR>G<------------------------------160
KCNH5------------------------------>-<------------------------------
KCNH6------------------------------>-<------------------------------
KCNH7RQWDRLYPDMLQSS------SQL----SHS>R<SRESLCSIRRASSVHDIEGFGVHPKNIFRD292
KCNH8---------------------VK----GRS>R<------------------------------155
CNGA1------------------------------>-<------------------------------
CNGA2------------------------------>-<------------------------------
CNGA3------------------------------>-<------------------------------
CNGA4------------------------------>-<------------------------------
CNGB1--------DTLIVPSSASGTHRKKLPSEDD>E<A-E---------ELKALSPAESPVVAWSDP541
CNGB3------------VP---------------->-<------------EQKEMDPGKE------GP111
HCN1------------------------------>-<------------------------------
HCN2------------------------------>-<------------------------------
HCN3------------------------------>-<------------------------------
HCN4------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNH2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.Arg271Hisc.812G>A UnknownSIFT:
Polyphen: