Paralogue Annotation for KCNH2 residue 285

Residue details

Gene: KCNH2
Reference Sequences: LRG: LRG_288, Ensembl variant: ENST00000262186 / ENSP00000262186
Amino Acid Position: 285
Reference Amino Acid: A - Alanine
Protein Domain: N-terminus


Paralogue Variants mapped to KCNH2 residue 285

No paralogue variants have been mapped to residue 285 for KCNH2.



KCNH2------CSL----ARTRSRESCASVRRASS>A<DDIEAM--------RAGVLPPPPRHASTGA307
KCNH1------------------------------>-<------------------------------
KCNH3-------RY----GRAR------------->-<------------------------------159
KCNH4-------SL----GRRG------------->-<------------------------------160
KCNH5------------------------------>-<------------------------------
KCNH6------------------------------>-<------------------------------
KCNH7------SQL----SHSRSRESLCSIRRASS>V<HDIEGFGVHPKNIFRDRHASEDNGRNVKGP306
KCNH8-------VK----GRSR------------->-<------------------------------155
CNGA1------------------------------>-<------------------------------
CNGA2------------------------------>-<------------------------------
CNGA3------------------------------>-<------------------------------
CNGA4------------------------------>-<------------------------------
CNGB1SSASGTHRKKLPSEDDEA-E---------E>L<KALSPAESPVVAWSDPTTPKDTDGQDRAAS555
CNGB3-----------------------------E>Q<KEMDPGKE------GPNSPQNK------PP119
HCN1------------------------------>-<------------------------------
HCN2------------------------------>-<------------------------------
HCN3------------------------------>-<------------------------------
HCN4------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNH2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.Ala285Thrc.853G>A UnknownSIFT:
Polyphen:
p.Ala285Serc.853G>T UnknownSIFT:
Polyphen: