Paralogue Annotation for KCNH2 residue 52

Residue details

Gene: KCNH2
Reference Sequences: LRG: LRG_288, Ensembl variant: ENST00000262186 / ENSP00000262186
Amino Acid Position: 52
Reference Amino Acid: C - Cysteine
Protein Domain: N-terminus


Paralogue Variants mapped to KCNH2 residue 52

No paralogue variants have been mapped to residue 52 for KCNH2.



KCNH2----FIIANA-RVEN-CAVI-YCNDGFCEL>C<GYSRAEVMQRPCTCDFLHGPRTQRRAAAQ-81
KCNH1----FVLGNA-QIVD-WPIV-YSNDGFCKL>S<GYHRAEVMQKSSTCSFMYGELTDKDTIEK-82
KCNH3----FVLGNA-QVAGLFPVV-YCSDGFCDL>T<GFSRAEVMQRGCACSFLYGPDTSELVRQQ-82
KCNH4----FLLANA-QGTRGFPIV-YCSDGFCEL>T<GYGRTEVMQKTCSCRFLYGPETSEPALQR-82
KCNH5----FLLGNA-QIVD-WPVV-YSNDGFCKL>S<GYHRADVMQKSSTCSFMYGELTDKKTIEK-80
KCNH6----FLIANA-QMEN-CAII-YCNDGFCEL>F<GYSRVEVMQQPCTCDFLTGPNTPSSAVSR-81
KCNH7----FIIANA-RVQN-CAII-YCNDGFCEM>T<GFSRPDVMQKPCTCDFLHGPETKRHDIAQ-81
KCNH8----FILANA-QVAKGFPIV-YCSDGFCEL>A<GFARTEVMQKSCSCKFLFGVETNEQLMLQ-82
CNGA1--I----------------R-RMEN----->-<----------------------------G-37
CNGA2----------------------NHNHHA-->-<---PPA-----------IKANGK-DDHRT-34
CNGA3--L----------------KVKTSD----->-<-----------------RDLNRA-EN--G-31
CNGA4------------------------------>-<------------------------------
CNGB1RVLTWLMKGVEKVIP-QPVH-SITE----->-<----------DPAQILGHGSTGDTGCTDE-142
CNGB3------------------------------>-<------------------------------
HCN1------------------------------>-<------------------------------
HCN2------------------------------>-<------------------------------
HCN3------------------------------>-<------------------------------
HCN4-----------------------EDAEEEG>-<AGGRQDPSRRSIRLRPLPSPSPSAAAGGTE66
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNH2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.C52Wc.156C>G Putative BenignSIFT:
Polyphen: