Paralogue Annotation for KCNH2 residue 77

Residue details

Gene: KCNH2
Reference Sequences: LRG: LRG_288, Ensembl variant: ENST00000262186 / ENSP00000262186
Amino Acid Position: 77
Reference Amino Acid: R - Arginine
Protein Domain: N-terminus


Paralogue Variants mapped to KCNH2 residue 77

No paralogue variants have been mapped to residue 77 for KCNH2.



KCNH2GFCELCGYSRAEVMQRPCTCDFLHGPRTQR>R<AAAQ-IAQ----------------------84
KCNH1GFCKLSGYHRAEVMQKSSTCSFMYGELTDK>D<TIEK-VRQ----------------------85
KCNH3GFCDLTGFSRAEVMQRGCACSFLYGPDTSE>L<VRQQ-IRK----------------------85
KCNH4GFCELTGYGRTEVMQKTCSCRFLYGPETSE>P<ALQR-LHK----------------------85
KCNH5GFCKLSGYHRADVMQKSSTCSFMYGELTDK>K<TIEK-VRQ----------------------83
KCNH6GFCELFGYSRVEVMQQPCTCDFLTGPNTPS>S<AVSR-LAQ----------------------84
KCNH7GFCEMTGFSRPDVMQKPCTCDFLHGPETKR>H<DIAQ-IAQ----------------------84
KCNH8GFCELAGFARTEVMQKSCSCKFLFGVETNE>Q<LMLQ-IEK----------------------85
CNGA1------------------------------>-<---G-ACS----------------------40
CNGA2HHA------PPA-----------IKANGK->D<DHRT-SSR----------------------37
CNGA3-----------------------RDLNRA->E<N--G-LSR----------------------34
CNGA4------------------------------>-<------------------------------
CNGB1----------------DPAQILGHGSTGDT>G<CTDE-PNE----------------------145
CNGB3------------------------------>-<------------------------------
HCN1------------------------------>-<------------------------------
HCN2------------------------------>-<------------------------------
HCN3------------------------------>-<------------------------------
HCN4AEEEG-AGGRQDPSRRSIRLRPLPSPSPSA>A<AGGTESRSSALGAADSEGPARGAGKSSTNG91
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNH2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.R77Sc.229C>A Putative BenignSIFT:
Polyphen: