Paralogue Annotation for KCNH2 residue 859

Residue details

Gene: KCNH2
Reference Sequences: LRG: LRG_288, Ensembl variant: ENST00000262186 / ENSP00000262186
Amino Acid Position: 859
Reference Amino Acid: T - Threonine
Protein Domain: C-terminus


Paralogue Variants mapped to KCNH2 residue 859

No paralogue variants have been mapped to residue 859 for KCNH2.



KCNH2HKIHRDDLLEVLDMYPEFSDHFWSSL--EI>T<-FNLRDTNM-IP-GSP---GSTELE-----878
KCNH1HVIKRDALQKVLEFYTAFSHSFSRNL--IL>T<-YNLRKRIV-FRKISD---VKREEE-----718
KCNH3QCLQLAGLHDSLALYPEFAPRFSRGLRGEL>S<-YNLGAGGG-SAEVDT-----SSLS-----719
KCNH4QQLSSRGLAEVLRLYPEYGAAFRAGLPRDL>T<-FNLRQGSD-TSGLSR-----FSRS-----703
KCNH5HIIKREALLKVLDFYTAFANSFSRNL--TL>T<-CNLRKRII-FRKISD---VKKEEE-----687
KCNH6HKIQRADLLEVLDMYPAFAESFWSKL--EV>T<-FNLRDAAG-GL-------HSSPRQ-----727
KCNH7HKIQREDLLEVLDMYPEFSDHFLTNL--EL>T<-FNLRHESA-KA-DLLRSQSMNDSE-----884
KCNH8QCIILKGLFEVLDLYPEYAHKFVEDIQHDL>T<-YNLREGHE-SDVISR-----LSNK-----688
CNGA1FCLSKDDLMEALTEYPDAKTMLEEKGKQIL>M<KDGLLDLNI-ANAGSD---PKDLEE-----625
CNGA2FCLSKDDLMEAVTEYPDAKKVLEERGREIL>M<KEGLLDENE-VATS-M---EVDVQE-----599
CNGA3FCLSKDDLMEALTEYPEAKKALEEKGRQIL>M<KDNLIDEEL-ARAGAD---PKDLEE-----628
CNGA4FCLSKEDLREVLSEYPQAQTIMEEKGREIL>L<KMNKLDVNA-EAAEIA---LQEATE-----494
CNGB1FILDKKDLNEILVHYPESQKLLRKKARRML>R<SNNKPK------EE-K-----SVLILPPRA1103
CNGB3LTLDKKTLQEILVHYPDSERILMKKARVLL>K<QKAKTA-EATPPRK-D-----LALLFPPKE670
HCN1YSLSVDNFNEVLEEYPMMRRAFETVAIDRL>D<RIGKKNSIL-LQKFQ------KDLNT----611
HCN2YSLSVDNFNEVLEEYPMMRRAFETVAIDRL>D<RIGKKNSIL-LHKVQ------HDLNS----680
HCN3YSLSVDHFNAVLEEFPMMRRAFETVAMDRL>L<RIGKKNSIL-QRKRS------EPSPG----564
HCN4YSLSVDNFNEVLEEYPMMRRAFETVALDRL>D<RIGKKNSIL-LHKVQ------HDLNS----731
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNH2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.Thr859Ilec.2576C>T UnknownSIFT:
Polyphen: