Paralogue Annotation for KCNH2 residue 9

Residue details

Gene: KCNH2
Reference Sequences: LRG: LRG_288, Ensembl variant: ENST00000262186 / ENSP00000262186
Amino Acid Position: 9
Reference Amino Acid: A - Alanine
Protein Domain: N-terminus

Paralogue Variants mapped to KCNH2 residue 9

No paralogue variants have been mapped to residue 9 for KCNH2.

KCNH2	--------------------RR----G-HV>A<PQNTFLDTI---IR----KFEGQSRK----	28
KCNH1	--------------------RR----G-LV>A<PQNTFLENI---VR----RS--NDTN----	29
KCNH3	--------------------MR----G-LL>A<PQNTFLDTI---AT----RFDGTHSN----	28
KCNH4	--------------------MK----G-LL>A<PQNTFLDTI---AT----RFDGTHSN----	28
KCNH5	--------------------KR----G-LV>A<PQNTFLENI---VR----RS--SESS----	27
KCNH6	--------------------RR----G-HV>A<PQNTYLDTI---IR----KFEGQSRK----	28
KCNH7	--------------------RR----G-HV>A<PQNTFLGTI---IR----KFEGQNKK----	28
KCNH8	--------------------MK----G-LL>A<PQNTFLDTI---AT----RFDGTHSN----	28
CNGA1	--------------------SMK---NNII>N<TQQSFVTMPNVIVP----DIEKE-------	30
CNGA2	--------------------K--------T>N<GVK--------SSP----AN----------	14
CNGA3	-----------------------------I>N<TQY--------SHP----SRTH--------	15
CNGA4	------------------------------>-<------------------------------
CNGB1	EAETESESMPPEESFKEEEVAV-----ADP>S<PQETKEAAL---TSTISLRAQGAEISEMNS	97
CNGB3	------------------------------>-<------------------------------
HCN1	--------------------G--------->-<-------------------GKPNS------	9
HCN2	------------------------------>-<------RG-----G----GGRPGE------	12
HCN3	--------------------E--------->-<-------------------QRPAA------	9
HCN4	--------------------LPPSMRKRLY>S<LPQQVGAK-----A----WIMDEE------	29
cons	> <

See full Alignment of Paralogues

Known Variants in KCNH2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.Ala9Val	c.26C>T	Unknown			SIFT: Polyphen: