Paralogue Annotation for KCNH2 residue 966

Residue details

Gene: KCNH2
Reference Sequences: LRG: LRG_288, Ensembl variant: ENST00000262186 / ENSP00000262186
Amino Acid Position: 966
Reference Amino Acid: E - Glutamate
Protein Domain: C-terminus


Paralogue Variants mapped to KCNH2 residue 966

No paralogue variants have been mapped to residue 966 for KCNH2.



KCNH2SSEDEGP---GRSSSPLRLVPFSSP-RPPG>E<PPGGEPLMEDC-------------------977
KCNH1SLVKASV---VTVRESPATPVSFQA-ASTS>G<VPDHAKLQAPGS------------------819
KCNH3TAPRPRL---GGRGRPGRAGALKAE-AGPS>A<PPRALEG-----------------------806
KCNH4ALVSSPS---LSPSLSPALAGQGHS-ASPH>G<PPRCSAAWKPPQ------------------809
KCNH5SVVTVSQ---ITPIQTSLAYVKTSE-SLKQ>N<NRDAMELKPNGG------------------789
KCNH6SISDASG---LWPELLQEMPPRHSP-QSPQ>E<DPDCWPLKLGSR------------------825
KCNH7SIDDEQK---PLFSGIVDSSPGIGK-ASGL>D<FEETVPTSGRMH------------------978
KCNH8SGT-VPF---HSPIRVSRSNSPKTK-QEID>P<PNHNKRKEKNLK------------------795
CNGA1AESGPID---S------------------->-<------------------------------689
CNGA2PELAAAD---E------------------->-<------------------------------663
CNGA3ATKTEDK---Q------------------->-<------------------------------693
CNGA4PEEGTSK---DE------------------>-<------------------------------562
CNGB1GSAAPDQ-----------HTHPKEA----->-<------------------------------1179
CNGB3EDKQKEN-----------EDKGKE------>-<------------------------------736
HCN1TSLSHSNL-H--------S----------->-<------------------------------680
HCN2PQVARPLVGP-------------------->-<------------------------------749
HCN3VAIALTHQRG--------P----------->-<------------------------------630
HCN4VAIALTHHPRLPAAIFRPPPGSGLGNLGAG>Q<TPRHLKRLQSLIPSALGSASPASSPSQVDT851
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNH2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.E966Ac.2897A>C Putative BenignSIFT:
Polyphen:
p.E966Kc.2896G>A Putative BenignSIFT:
Polyphen: