Paralogue Annotation for KCNH2 residue 97

Residue details

Gene: KCNH2
Reference Sequences: LRG: LRG_288, Ensembl variant: ENST00000262186 / ENSP00000262186
Amino Acid Position: 97
Reference Amino Acid: A - Alanine
Protein Domain: N-terminus


Paralogue Variants mapped to KCNH2 residue 97

No paralogue variants have been mapped to residue 97 for KCNH2.



KCNH2------------GAEE-R-------KVE-I>A<FYRK-----------DGS------------104
KCNH1------------NYEM-N-------SFE-I>L<MYKK-----------NRT------------105
KCNH3------------EHKE-F-------KAE-L>I<LYRK-----------SGL------------105
KCNH4------------GHQE-H-------RAE-I>C<FYRK-----------DGS------------105
KCNH5------------NYES-N-------CFE-V>L<LYKK-----------NRT------------103
KCNH6------------GAEE-C-------KVD-I>L<YYRK-----------DAS------------104
KCNH7------------GSEE-R-------KVE-V>T<YYHK-----------NGS------------104
KCNH8------------EKTE-F-------KGE-I>M<FYKK-----------NGS------------105
CNGA1------------EDDD-SASTSEESENEN->P<HA-R-----------GSF------------66
CNGA2------------AADDDTSSE--------->L<QR-L-----------ADV------------56
CNGA3------------SSEE-TSSVLQPGIAME->T<RG-L-----------ADS------------60
CNGA4------------------------------>-<------------------------------
CNGB1------------AQDT-R-------PGLRL>L<LWLEQNLERVLPQPPKSSEVWRDEPAVATG189
CNGB3------------------------------>-<------------------------------
HCN1KRLGTPPGGGGAGAKE-H-------GNS-V>C<FKVD--------------------------62
HCN2GRGEPQCSPAGPEGPA-R-------GPK-V>S<FSCR--------------------------128
HCN3------------------------------>A<PPPA--------------------------30
HCN4------------------------------>-<ASCE--------------------------180
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNH2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.A97Sc.289G>T Putative BenignSIFT: tolerated
Polyphen: benign
p.Ala97Glyc.290C>G UnknownSIFT:
Polyphen: