Paralogue Annotation for KCNH2 residue 979

Residue details

Gene: KCNH2
Reference Sequences: LRG: LRG_288, Ensembl variant: ENST00000262186 / ENSP00000262186
Amino Acid Position: 979
Reference Amino Acid: K - Lysine
Protein Domain: C-terminus

Paralogue Variants mapped to KCNH2 residue 979

No paralogue variants have been mapped to residue 979 for KCNH2.

KCNH2	-----------------------------E>K<SSDTCNPLSG-AFSGVSNIFS---------	999
KCNH1	----------------------------EC>L<GPKGGGGDCAK----RKSWAR---------	839
KCNH3	----------------------------LR>L<PPMPWNVPPDLSPRVVDGIED---------	830
KCNH4	----------------------------LL>I<PPLGTFGPPDLSPRIVDGIED---------	833
KCNH5	----------------------------AD>Q<KCLKVNSPIRMKNGNGKGWLR---------	813
KCNH6	----------------------------LE>Q<LQAQMNRLESRVSSDLSRILQ---------	849
KCNH7	----------------------------ID>K<RSHSCKDITDMRSWERENAHP---------	1002
KCNH8	----------------------------LQ>L<STLNNAGPPDLSPRIVDGIED---------	819
CNGA1	------------------------------>-<------------------------------
CNGA2	------------------------------>-<------------------------------
CNGA3	------------------------------>-<------------------------------
CNGA4	------------------------------>-<------------E-----------------	563
CNGB1	------------------------------>-<----------------A-------------	1180
CNGB3	------------------------------>-<----------------N-------------	737
HCN1	------------SPCSYTTAVCSPPVQSPL>A<ARTFHYASPTASQLSLMQ------------	731
HCN2	-----------RPPPGPAPAAASPG----->-<------PPPPASP-----------------	780
HCN3	-----------RSAWRSAGSPASPL----->-<------VPVRAGPWASTS------------	669
HCN4	SPLLTPLQPGARSPQAAQPSPAPPGARGGL>G<LPEHFLPPPPSSRSPSSSPGQLGQPPGELS	983
cons	> <

See full Alignment of Paralogues

Known Variants in KCNH2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.K979R	c.2936A>G	Putative Benign			SIFT: Polyphen: