Paralogue Annotation for KCNJ2 residue 118

Residue details

Gene: KCNJ2
Reference Sequences: LRG: LRG_328, Ensembl variant: ENST00000535240 / ENSP00000441848
Amino Acid Position: 118
Reference Amino Acid: E - Glutamate
Protein Domain: Transmembrane region

Paralogue Variants mapped to KCNJ2 residue 118

No paralogue variants have been mapped to residue 118 for KCNJ2.

KCNJ2	LLHGDLDAS--------------------K>E<GKACVSEVNSFTAAFLFSIETQTTIGYGFR	148
KCNJ1	YIHKDLPEF--HP---------------SA>N<HTPCVENINGLTSAFLFSLETQVTIGYGFR	147
KCNJ3	YTRGDLNKA--HV----------------G>N<YTPCVANVYNFPSAFLFFIETEATIGYGYR	149
KCNJ4	FFHGDLEAS--PGVPAAGGPAAGGGGAAPV>A<PKPCIMHVNGFLGAFLFSVETQTTIGYGFR	140
KCNJ5	YIRGDLDHV--GD----------------Q>E<WIPCVENLSGFVSAFLFSIETETTIGYGFR	155
KCNJ6	YIRGDMDHI--ED----------------P>S<WTPCVTNLNGFVSAFLFSIETETTIGYGYR	158
KCNJ8	FAHGDIYAY--MEKS--G------MEKSGL>E<STVCVTNVRSFTSAFLFSIEVQVTIGFGGR	146
KCNJ9	YGRGDLEHL--ED----------------T>A<WTPCVNNLNGFVAAFLFSIETETTIGYGHR	126
KCNJ10	VAHGDLLEL--DP---------------PA>N<HTPCVVQVHTLTGAFLFSLESQTTIGYGFR	134
KCNJ11	FAHGDLAP----S-E------------GTA>-<-EPCVTSIHSFSSAFLFSIEVQVTIGFGGR	136
KCNJ12	VAHGDLEPA--EG----------------R>G<RTPCVMQVHGFMAAFLFSIETQTTIGYGLR	149
KCNJ13	EMNGDLELDHDAP---------------PE>N<HTICVKYITSFTAAFSFSLETQLTIGYGTM	125
KCNJ14	SLHGDLAAP--P------------------>P<PAPCFSHVASFLAAFLFALETQTSIGYGVR	153
KCNJ15	FIHGDLEPG--EP---------------IS>N<HTPCIMKVDSLTGAFLFSLESQTTIGYGVR	133
KCNJ16	FHHGDLLND--P------------------>D<ITPCVDNVHSFTGAFLFSLETQTTIGYGYR	137
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See full Alignment of Paralogues

Known Variants in KCNJ2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.E118D	c.354G>C	Putative Benign			SIFT: tolerated Polyphen: benign