Paralogue Annotation for KCNJ2 residue 281

Residue details

Gene: KCNJ2
Reference Sequences: LRG: LRG_328, Ensembl variant: ENST00000535240 / ENSP00000441848
Amino Acid Position: 281
Reference Amino Acid: D - Aspartate
Protein Domain: C-terminus

Paralogue Variants mapped to KCNJ2 residue 281

No paralogue variants have been mapped to residue 281 for KCNJ2.

KCNJ2	GFD--SGIDRIFLVSPITIVHEIDEDSPLY>D<LSKQDID-NADFEIVVILEGMVEATAMTTQ	310
KCNJ1	VVD--AGNENLFFISPLTIYHVIDHNSPFF>H<MAAETLL-QQDFELVVFLDGTVESTSATCQ	309
KCNJ3	GFS--TGADQLFLVSPLTICHVIDAKSPFY>D<LSQRSMQ-TEQFEIVVILEGIVETTGMTCQ	311
KCNJ4	GYD--IGLDRIFLVSPIIIVHEIDEDSPLY>G<MGKEELE-SEDFEIVVILEGMVEATAMTTQ	302
KCNJ5	GFD--TGDDRLFLVSPLIISHEINQKSPFW>E<MSQAQLH-QEEFEVVVILEGMVEATGMTCQ	317
KCNJ6	GYY--TGDDRLFLVSPLIISHEINQQSPFW>E<ISKAQLP-KEELEIVVILEGMVEATGMTCQ	320
KCNJ8	DNP--IESNNIFLVAPLIICHVIDKRSPLY>D<ISATDLA-NQDLEVIVILEGVVETTGITTQ	308
KCNJ9	GFD--TGDDRLFLVSPLVISHEIDAASPFW>E<ASRRALE-RDDFEIVVILEGMVEATGMTCQ	288
KCNJ10	QVD--TASDSPFLILPLTFYHVVDETSPLK>D<LPLRSG--EGDFELVLILSGTVESTSATCQ	295
KCNJ11	ENG--VGGNSIFLVAPLIIYHVIDANSPLY>D<LAPSDLHHHQDLEIIVILEGVVETTGITTQ	299
KCNJ12	GFD--KGLDRIFLVSPITILHEIDEASPLF>G<ISRQDLE-TDDFEIVVILEGMVEATAMTTQ	311
KCNJ13	HLDGISSDECPFFIFPLTYYHSITPSSPLA>T<LLQHE-N-PSHFELVVFLSAMQEGTGEICQ	283
KCNJ14	GFD--GGTDRIFLVSPITIVHEIDSASPLY>E<LGRAELA-RADFELVVILEGMVEATAMTTQ	315
KCNJ15	HVD--SSSESPFLILPMTFYHVLDETSPLR>D<LTPQNLK-EKEFELVVLLNATVESTSAVCQ	295
KCNJ16	V------NDQIILVTPVTIVHEIDHESPLY>A<LDRKAVA-KDNFEILVTFIYTGDSTGTSHQ	294
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See full Alignment of Paralogues

Known Variants in KCNJ2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.D281A	c.842A>C	Putative Benign			SIFT: tolerated Polyphen: benign