Paralogue Annotation for KCNJ2 residue 40

Residue details

Gene: KCNJ2
Reference Sequences: LRG: LRG_328, Ensembl variant: ENST00000535240 / ENSP00000441848
Amino Acid Position: 40
Reference Amino Acid: R - Arginine
Protein Domain: N-terminus

Paralogue Variants mapped to KCNJ2 residue 40

No paralogue variants have been mapped to residue 40 for KCNJ2.

KCNJ2	SSEEDGM--KLATMAVANGF-GNGKSKVHT>R<QQCRSRFVKKDGHCNVQFINVGEKGQ--RY	68
KCNJ1	LTESMFK--HLRK------W-VVT-R-FFG>H<SRQRARLVSKDGRCNIEFGNVEA-QSRFIF	64
KCNJ3	SSSGS----GLQPQG--PGQ-D-PQQQLV->P<KKKRQRFVDKNGRCNVQHGNLGSETS--RY	67
KCNJ4	----------------------NGQAHVP->R<RKRRNRFVKKNGQCNVYFANLSNKSQ--RY	42
KCNJ5	PWDPKKIPKQARDYV--PIATD-RTRLLAE>G<KKPRQRYMEKSGKCNVHHGNVQ-ETY--RY	73
KCNJ6	IHQP-KLPKQARDDL--PRHIS-RDR---->T<KRKIQRYVRKDGKCNVHHGNVR-ETY--RY	76
KCNJ8	RIAA---------------E-NLRKP-RIR>D<RLPKARFIAKSGACNLAHKNIR-EQG--RF	56
KCNJ9	AFSP-------------------GQE-EPP>R<RRGRQRYVEKDGRCNVQQGNVR-ETY--RY	44
KCNJ10	TQTES------------------R-P-LMG>P<GIRRRRVLTKDGRSNVRMEHIADKRF--LY	51
KCNJ11	RLA----------------E-DPAKP-RYR>A<RQRRARFVSKKGNCNVAHKNIR-EQG--RF	55
KCNJ12	SSEEDGL--HLVTMSGANGF-GNGK--VHT>R<RRCRNRFVKKNGQCNIEFANMDEKSQ--RY	67
KCNJ13	MDSSNCK--VIAP------L-L-------->-<SQRYRRMVTKDGHSTLQMDGAQR-GL--AY	40
KCNJ14	DEEEAGP--GLCRNGWAPAP-VQS----P->V<GRRRGRFVKKDGHCNVRFVNLGGQGA--RY	73
KCNJ15	PLVKH------------------T-A-GAG>L<KANRPRVMSKSGHSNVRIDKVDGIYL--LY	50
KCNJ16	NADAKYP-----------GY-PPEH-IIAE>K<RRARRRLLHKDGSCNVYFKHIFGEWG--SY	57
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See full Alignment of Paralogues

Known Variants in KCNJ2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.R40Q	c.119G>A	Putative Benign			SIFT: Polyphen: