Paralogue Annotation for KCNJ2 residue 408

Residue details

Gene: KCNJ2
Reference Sequences: LRG: LRG_328, Ensembl variant: ENST00000535240 / ENSP00000441848
Amino Acid Position: 408
Reference Amino Acid: L - Leucine
Protein Domain: C-terminus


Paralogue Variants mapped to KCNJ2 residue 408

No paralogue variants have been mapped to residue 408 for KCNJ2.



KCNJ2-------------------------PPDID>L<------HNQASVPLEPRPLRRESEI427
KCNJ1------------------------------>-<---------PNFILSEVNETDDTKM391
KCNJ3NSEEKLVSKTTKMLSDPMSQSVADLPPKLQ>K<MAGGAARMEGNLPAKLRKMNSDRFT501
KCNJ4----AGI----------IRMLEFGSHLDLE>-<------RMQASLPLDNISYRRESAI445
KCNJ5------------------------------>-<GLGGSR-------------EARGSV419
KCNJ6------------------------------>-<GDVANL-------------ENESKV423
KCNJ8---------------------------NSS>-<-----LMVPKVQFMTPEGNQNTSES424
KCNJ9------------------------------>-<GCLPPP-------------ESESKV393
KCNJ10------------------------------>-<---------AEKEGSALSVRISN-V379
KCNJ11------------------------------>-<-------VPMAKAKPKFSISPDSLS390
KCNJ12--------------------LSPQARHDFD>R<------LQAGGGVLEQRPYRRESEI433
KCNJ13------------------------------>-<----------NFQISETGLT----E360
KCNJ14--------------------EDG------->-<--------AASPRVLTPTLALTLPP436
KCNJ15------------------------------>-<---------RERELRTLLLQQSN-V375
KCNJ16-------------------------THEYR>E<------TPYQKALLTLNRISVESQM418
cons                              > <                         

See full Alignment of Paralogues


Known Variants in KCNJ2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.L408Vc.1222C>G Putative BenignSIFT:
Polyphen: