Paralogue Annotation for KCNJ2 residue 410

Residue details

Gene: KCNJ2
Reference Sequences: LRG: LRG_328, Ensembl variant: ENST00000535240 / ENSP00000441848
Amino Acid Position: 410
Reference Amino Acid: N - Asparagine
Protein Domain: C-terminus

Paralogue Variants mapped to KCNJ2 residue 410

No paralogue variants have been mapped to residue 410 for KCNJ2.

KCNJ2	-----------------PPDIDL------H>N<QASVPLEPRPLRRESEI	427
KCNJ1	------------------------------>-<-PNFILSEVNETDDTKM	391
KCNJ3	KTTKMLSDPMSQSVADLPPKLQKMAGGAAR>M<EGNLPAKLRKMNSDRFT	501
KCNJ4	---------IRMLEFGSHLDLE-------R>M<QASLPLDNISYRRESAI	445
KCNJ5	-----------------------GLGGSR->-<-----------EARGSV	419
KCNJ6	-----------------------GDVANL->-<-----------ENESKV	423
KCNJ8	-------------------NSS------LM>V<PKVQFMTPEGNQNTSES	424
KCNJ9	-----------------------GCLPPP->-<-----------ESESKV	393
KCNJ10	------------------------------>-<-AEKEGSALSVRISN-V	379
KCNJ11	------------------------------>V<PMAKAKPKFSISPDSLS	390
KCNJ12	------------LSPQARHDFDR------L>Q<AGGGVLEQRPYRRESEI	433
KCNJ13	------------------------------>-<--NFQISETGLT----E	360
KCNJ14	------------EDG--------------->-<AASPRVLTPTLALTLPP	436
KCNJ15	------------------------------>-<-RERELRTLLLQQSN-V	375
KCNJ16	-----------------THEYRE------T>P<YQKALLTLNRISVESQM	418
cons	> <

See full Alignment of Paralogues

Known Variants in KCNJ2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.N410Y	c.1228A>T	Putative Benign		rs111909178	SIFT: tolerated Polyphen: benign
p.N410S	c.1229A>G	Inherited Arrhythmia	LQTS	rs141069645	SIFT: tolerated Polyphen: benign