Paralogue Annotation for KCNJ2 residue 420

Residue details

Gene: KCNJ2
Reference Sequences: LRG: LRG_328, Ensembl variant: ENST00000535240 / ENSP00000441848
Amino Acid Position: 420
Reference Amino Acid: P - Proline
Protein Domain: C-terminus


Paralogue Variants mapped to KCNJ2 residue 420

No paralogue variants have been mapped to residue 420 for KCNJ2.



KCNJ2-------PPDIDL------HNQASVPLEPR>P<LRRESEI427
KCNJ1----------------------PNFILSEV>N<ETDDTKM391
KCNJ3SQSVADLPPKLQKMAGGAARMEGNLPAKLR>K<MNSDRFT501
KCNJ4RMLEFGSHLDLE-------RMQASLPLDNI>S<YRRESAI445
KCNJ5-------------GLGGSR----------->-<-EARGSV419
KCNJ6-------------GDVANL----------->-<-ENESKV423
KCNJ8---------NSS------LMVPKVQFMTPE>G<NQNTSES424
KCNJ9-------------GCLPPP----------->-<-ESESKV393
KCNJ10----------------------AEKEGSAL>S<VRISN-V379
KCNJ11--------------------VPMAKAKPKF>S<ISPDSLS390
KCNJ12--LSPQARHDFDR------LQAGGGVLEQR>P<YRRESEI433
KCNJ13-----------------------NFQISET>G<LT----E360
KCNJ14--EDG----------------AASPRVLTP>T<LALTLPP436
KCNJ15----------------------RERELRTL>L<LQQSN-V375
KCNJ16-------THEYRE------TPYQKALLTLN>R<ISVESQM418
cons                              > <       

See full Alignment of Paralogues


Known Variants in KCNJ2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.P420Lc.1259C>T Putative BenignSIFT: tolerated
Polyphen: benign