Paralogue Annotation for KCNJ2 residue 43

Residue details

Gene: KCNJ2
Reference Sequences: LRG: LRG_328, Ensembl variant: ENST00000535240 / ENSP00000441848
Amino Acid Position: 43
Reference Amino Acid: C - Cysteine
Protein Domain: N-terminus

Paralogue Variants mapped to KCNJ2 residue 43

No paralogue variants have been mapped to residue 43 for KCNJ2.

KCNJ2	EDGM--KLATMAVANGF-GNGKSKVHTRQQ>C<RSRFVKKDGHCNVQFINVGEKGQ--RYLAD	71
KCNJ1	SMFK--HLRK------W-VVT-R-FFGHSR>Q<RARLVSKDGRCNIEFGNVEA-QSRFIFFVD	67
KCNJ3	GS----GLQPQG--PGQ-D-PQQQLV-PKK>K<RQRFVDKNGRCNVQHGNLGSETS--RYLSD	70
KCNJ4	-------------------NGQAHVP-RRK>R<RNRFVKKNGQCNVYFANLSNKSQ--RYMAD	45
KCNJ5	PKKIPKQARDYV--PIATD-RTRLLAEGKK>P<RQRYMEKSGKCNVHHGNVQ-ETY--RYLSD	76
KCNJ6	P-KLPKQARDDL--PRHIS-RDR----TKR>K<IQRYVRKDGKCNVHHGNVR-ETY--RYLTD	79
KCNJ8	A---------------E-NLRKP-RIRDRL>P<KARFIAKSGACNLAHKNIR-EQG--RFLQD	59
KCNJ9	P-------------------GQE-EPPRRR>G<RQRYVEKDGRCNVQQGNVR-ETY--RYLTD	47
KCNJ10	ES------------------R-P-LMGPGI>R<RRRVLTKDGRSNVRMEHIADKRF--LYLKD	54
KCNJ11	----------------E-DPAKP-RYRARQ>R<RARFVSKKGNCNVAHKNIR-EQG--RFLQD	58
KCNJ12	EDGL--HLVTMSGANGF-GNGK--VHTRRR>C<RNRFVKKNGQCNIEFANMDEKSQ--RYLAD	70
KCNJ13	SNCK--VIAP------L-L---------SQ>R<YRRMVTKDGHSTLQMDGAQR-GL--AYLRD	43
KCNJ14	EAGP--GLCRNGWAPAP-VQS----P-VGR>R<RGRFVKKDGHCNVRFVNLGGQGA--RYLSD	76
KCNJ15	KH------------------T-A-GAGLKA>N<RPRVMSKSGHSNVRIDKVDGIYL--LYLQD	53
KCNJ16	AKYP-----------GY-PPEH-IIAEKRR>A<RRRLLHKDGSCNVYFKHIFGEWG--SYVVD	60
cons	> <

See full Alignment of Paralogues

Known Variants in KCNJ2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.C43Y	c.128G>A	Putative Benign			SIFT: Polyphen: