Paralogue Annotation for KCNJ2 residue 5

Residue details

Gene: KCNJ2
Reference Sequences: LRG: LRG_328, Ensembl variant: ENST00000535240 / ENSP00000441848
Amino Acid Position: 5
Reference Amino Acid: R - Arginine
Protein Domain: N-terminus

Paralogue Variants mapped to KCNJ2 residue 5

No paralogue variants have been mapped to residue 5 for KCNJ2.

KCNJ2	-MGSV>R<-------------TNRYSIV--SSEEDGM-	19
KCNJ1	MNASS>R<-------------NVFDTLIRVLTESMFK-	22
KCNJ3	MSALR>R<K---------FGDDYQVVTT--SSSGS---	22
KCNJ4	MHGHS>R<------------------------------	6
KCNJ5	MAGDS>R<--------NAMNQDMEIGVT--PWDPKKIP	26
KCNJ6	MAKLT>E<SMTNVLEGDSMDQDVESPVA--IHQP-KLP	33
KCNJ8	MLARK>S<-----------IIPEEYVLA--RIAA----	19
KCNJ9	----->-<--------------MAQENA--AFSP----	10
KCNJ10	-MTSV>A<-------------KVYYSQT--TQTES---	17
KCNJ11	MLSRK>G<-----------IIPEEYVLT--RLA-----	18
KCNJ12	MTAAS>R<-------------ANPYSIV--SSEEDGL-	20
KCNJ13	----->-<----------------------MDSSNCK-	7
KCNJ14	-MGLA>R<ALR---RLSGALDSGDSRAG--DEEEAGP-	29
KCNJ15	--MDA>I<-------------HIGMSST--PLVKH---	16
KCNJ16	--MSY>Y<-------------GSSYHII--NADAKYP-	18
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See full Alignment of Paralogues

Known Variants in KCNJ2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.R5G	c.13C>G	Putative Benign		rs1042485	SIFT: deleterious Polyphen: possibly damaging
p.R5Q	c.14G>A	Putative Benign			SIFT: Polyphen: