Paralogue Annotation for KCNJ2 residue 70

Residue details

Gene: KCNJ2
Reference Sequences: LRG: LRG_328, Ensembl variant: ENST00000535240 / ENSP00000441848
Amino Acid Position: 70
Reference Amino Acid: A - Alanine
Protein Domain: N-terminus

Paralogue Variants mapped to KCNJ2 residue 70

No paralogue variants have been mapped to residue 70 for KCNJ2.

KCNJ2	QCRSRFVKKDGHCNVQFINVGEKGQ--RYL>A<DIFTTCVDIRWRWMLVIFCLAFVLSWLFFG	100
KCNJ1	RQRARLVSKDGRCNIEFGNVEA-QSRFIFF>V<DIWTTVLDLKWRYKMTIFITAFLGSWFFFG	96
KCNJ3	KKRQRFVDKNGRCNVQHGNLGSETS--RYL>S<DLFTTLVDLKWRWNLFIFILTYTVAWLFMA	99
KCNJ4	KRRNRFVKKNGQCNVYFANLSNKSQ--RYM>A<DIFTTCVDTRWRYMLMIFSAAFLVSWLFFG	74
KCNJ5	KPRQRYMEKSGKCNVHHGNVQ-ETY--RYL>S<DLFTTLVDLKWRFNLLVFTMVYTVTWLFFG	105
KCNJ6	RKIQRYVRKDGKCNVHHGNVR-ETY--RYL>T<DIFTTLVDLKWRFNLLIFVMVYTVTWLFFG	108
KCNJ8	LPKARFIAKSGACNLAHKNIR-EQG--RFL>Q<DIFTTLVDLKWRHTLVIFTMSFLCSWLLFA	88
KCNJ9	RGRQRYVEKDGRCNVQQGNVR-ETY--RYL>T<DLFTTLVDLQWRLSLLFFVLAYALTWLFFG	76
KCNJ10	IRRRRVLTKDGRSNVRMEHIADKRF--LYL>K<DLWTTFIDMQWRYKLLLFSATFAGTWFLFG	83
KCNJ11	QRRARFVSKKGNCNVAHKNIR-EQG--RFL>Q<DVFTTLVDLKWPHTLLIFTMSFLCSWLLFA	87
KCNJ12	RCRNRFVKKNGQCNIEFANMDEKSQ--RYL>A<DMFTTCVDIRWRYMLLIFSLAFLASWLLFG	99
KCNJ13	QRYRRMVTKDGHSTLQMDGAQR-GL--AYL>R<DAWGILMDMRWRWMMLVFSASFVVHWLVFA	72
KCNJ14	RRRGRFVKKDGHCNVRFVNLGGQGA--RYL>S<DLFTTCVDVRWRWMCLLFSCSFLASWLLFG	105
KCNJ15	ANRPRVMSKSGHSNVRIDKVDGIYL--LYL>Q<DLWTTVIDMKWRYKLTLFAATFVMTWFLFG	82
KCNJ16	RARRRLLHKDGSCNVYFKHIFGEWG--SYV>V<DIFTTLVDTKWRHMFVIFSLSYILSWLIFG	89
cons	> <

See full Alignment of Paralogues

Known Variants in KCNJ2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.A70S	c.208G>T	Putative Benign		rs375605948	SIFT: tolerated Polyphen: benign
p.A70T	c.208G>A	Putative Benign			SIFT: Polyphen: