Paralogue Annotation for RYR1 residue 1431

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 1431
Reference Amino Acid: T - Threonine
Protein Domain:

Paralogue Variants mapped to RYR1 residue 1431

No paralogue variants have been mapped to residue 1431 for RYR1.

RYR1	PPATPTLPRLPHDVVPADNRDDPEIILNTT>T<YYYSVRVFAGQEPSCVWAGWVTPDYHQHDM	1461
RYR2	DYSTSHSARLTEDVLADDRDDYDFLMQT-S>T<YYYSVRIFPGQEPANVWVGWITSDFHQYDT	1455
RYR3	------SPCLDSEAFQKRKQMQEILSHTTT>Q<CYYAIRIFAGQDPSCVWVGWVTPDYHLYSE	1357
cons	> <

See full Alignment of Paralogues

Known Variants in RYR1

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.T1431M	c.4292C>T	Putative Benign		rs191656849	SIFT: Polyphen: probably damaging