Paralogue Annotation for RYR1 residue 1497

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 1497
Reference Amino Acid: G - Glycine
Protein Domain:

Paralogue Variants mapped to RYR1 residue 1497

No paralogue variants have been mapped to residue 1497 for RYR1.

RYR1	KVRVVTVTMGDEQGNVHSSLKCSNCYMVWG>G<DFVSPGQQGRISHTDLVIGCLVDLATGLMT	1527
RYR2	RVRTVTVTLGDEKGKVHESIKRSNCYMVCA>G<ESMSPGQ-G-RNNNGLEIGCVVDAASGLLT	1519
RYR3	KNCTVTVTLGDERGRVHESVKRSNCYMVWG>G<DIVASSQRSNRSNVDLEIGCLVDLAMGMLS	1423
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See full Alignment of Paralogues

Known Variants in RYR1

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.G1497R	c.4489G>A	Putative Benign		rs367637223	SIFT: deleterious Polyphen: probably damaging