Paralogue Annotation for RYR1 residue 1655

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 1655
Reference Amino Acid: R - Arginine
Protein Domain:

Paralogue Variants mapped to RYR1 residue 1655

No paralogue variants have been mapped to residue 1655 for RYR1.

RYR1	WAVQCQEPLTMMALHIPEENRCMDILELSE>R<LDLQRFHSHTLRLYRAVCALGNNRVAHALC	1685
RYR2	WLVQCLDPLQFMSLHIPEENRSVDILELTE>Q<EELLKFHYHTLRLYSAVCALGNHRVAHALC	1677
RYR3	WVVQCLEPLQMMALHIPEENRCVDILELCE>Q<EDLMRFHYHTLRLYSAVCALGNSRVAYALC	1581
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See full Alignment of Paralogues

Known Variants in RYR1

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.R1655C	c.4963C>T	Putative Benign		rs371777056	SIFT: tolerated Polyphen: probably damaging
p.R1655H	c.4964G>A	Putative Benign			SIFT: Polyphen: