Paralogue Annotation for RYR1 residue 1733

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 1733
Reference Amino Acid: Y - Tyrosine
Protein Domain:


Paralogue Variants mapped to RYR1 residue 1733

No paralogue variants have been mapped to residue 1733 for RYR1.



RYR1PGPLRAGYYDLLISIHLESACRSRRSMLSE>Y<IVPLTPETRAITLFPPGRSTENGHPRHGLP1763
RYR2PGLLRAGYYDLLIDIHLSSYATARLMMNNE>Y<IVPMTEETKSITLFPD------ENKKHGLP1749
RYR3PGLLRSGFYDLLISIHLASAKERKLMMKNE>Y<IIPITSTTRNIRLFPD------ESKRHGLP1653
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.Y1733Sc.5198A>C Putative BenignSIFT: deleterious
Polyphen: benign
p.Y1733Nc.5197T>A Putative BenignSIFT:
Polyphen: