Paralogue Annotation for RYR1 residue 1773

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 1773
Reference Amino Acid: P - Proline
Protein Domain:

Paralogue Variants mapped to RYR1 residue 1773

No paralogue variants have been mapped to residue 1773 for RYR1.

RYR1	AITLFPPGRSTENGHPRHGLPGVGVTTSLR>P<PHHFSPPCFVAALPAAGAAEAPARLSPAIP	1803
RYR2	SITLFPD------ENKKHGLPGIGLSTSLR>P<RMQFSSPSFVSI------SNECYQYSPEFP	1783
RYR3	NIRLFPD------ESKRHGLPGVGLRTCLK>P<GFRFSTPCFVVT------GEDHQKQSPEIP	1687
cons	> <

See full Alignment of Paralogues

Known Variants in RYR1

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.P1773S	c.5317C>T	Putative Benign		rs192863857	SIFT: Polyphen: probably damaging