Paralogue Annotation for RYR1 residue 2115

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 2115
Reference Amino Acid: E - Glutamate
Protein Domain:


Paralogue Variants mapped to RYR1 residue 2115

No paralogue variants have been mapped to residue 2115 for RYR1.



RYR1SAEESKPRSLQELVSHMVVRWAQEDFVQSP>E<LVRAMFSLLHRQYDGLGELLRALPRAYTIS2145
RYR2ESDSKKSSTLQQLISETMVRWAQESVIEDP>E<LVRAMFVLLHRQYDGIGGLVRALPKTYTIN2109
RYR3EEEERCPTTLKELISQTMICWAQEDQIQDS>E<LVRMMFNLLRRQYDSIGELLQALRKTYTIS2007
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.E2115Kc.6343G>A Putative BenignSIFT:
Polyphen: benign