Paralogue Annotation for RYR1 residue 220

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 220
Reference Amino Acid: R - Arginine
Protein Domain:


Paralogue Variants mapped to RYR1 residue 220

No paralogue variants have been mapped to residue 220 for RYR1.



RYR1ASFMQTLWNMNPICSR--CEEGFVTGGHVL>R<LFHGHMDECLTISPAD-SDDQRRLVYYEGG249
RYR2AAFQQTLWSVAPISSGSEAAQGYLIGGDVL>R<LLHGHMDECLTVPSGEHGEEQRRTVHYEGG265
RYR3ASFMQTLWNVHPTCSGSSIEEGYLLGGHVV>R<LFHGH-DECLTIPSTDQNDSQHRRIFYEAG254
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.R220Hc.659G>A Putative BenignSIFT:
Polyphen: