Paralogue Annotation for RYR1 residue 223

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 223
Reference Amino Acid: H - Histidine
Protein Domain:


Paralogue Variants mapped to RYR1 residue 223

No paralogue variants have been mapped to residue 223 for RYR1.



RYR1MQTLWNMNPICSR--CEEGFVTGGHVLRLF>H<GHMDECLTISPAD-SDDQRRLVYYEGGAVC252
RYR2QQTLWSVAPISSGSEAAQGYLIGGDVLRLL>H<GHMDECLTVPSGEHGEEQRRTVHYEGGAVS268
RYR3MQTLWNVHPTCSGSSIEEGYLLGGHVVRLF>H<GH-DECLTIPSTDQNDSQHRRIFYEAGGAG257
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.H223Rc.668A>G Putative BenignSIFT:
Polyphen: