Paralogue Annotation for RYR1 residue 3431

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 3431
Reference Amino Acid: A - Alanine
Protein Domain:

Paralogue Variants mapped to RYR1 residue 3431

No paralogue variants have been mapped to residue 3431 for RYR1.

RYR1	LCRDLYALYPLLIRYVDNNRAQWLTEPNPS>A<EELFRMVGEIFIYWSKSHNFKREEQNFVVQ	3461
RYR2	LARDLYAFYPLLIRFVDYNRAKWLKEPNPE>A<EELFRMVAEVFIYWSKSHNFKREEQNFVVQ	3422
RYR3	LCRDLYAFYPMLIRYVDNNRSNWLKSPDAD>S<DQLFRMVAEVFILWCKSHNFKREEQNFVIQ	3318
cons	> <

See full Alignment of Paralogues

Known Variants in RYR1

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.A3431T	c.10291G>A	Putative Benign			SIFT: tolerated Polyphen: benign
p.A3431V	c.10292C>T	Putative Benign			SIFT: Polyphen: