Paralogue Annotation for RYR1 residue 3453

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 3453
Reference Amino Acid: R - Arginine
Protein Domain:


Paralogue Variants mapped to RYR1 residue 3453

No paralogue variants have been mapped to residue 3453 for RYR1.



RYR1WLTEPNPSAEELFRMVGEIFIYWSKSHNFK>R<EEQNFVVQNEINNMSFLTADNKSKMAKAGD3483
RYR2WLKEPNPEAEELFRMVAEVFIYWSKSHNFK>R<EEQNFVVQNEINNMSFLITDTKSKMSKAA-3443
RYR3WLKSPDADSDQLFRMVAEVFILWCKSHNFK>R<EEQNFVIQNEINNLAFLTGDSKSKMSKAMQ3340
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.R3453Hc.10358G>A Putative BenignSIFT:
Polyphen: benign