Paralogue Annotation for RYR1 residue 3725

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 3725
Reference Amino Acid: Y - Tyrosine
Protein Domain:


Paralogue Variants mapped to RYR1 residue 3725

No paralogue variants have been mapped to residue 3725 for RYR1.



RYR1PDPLHQLVLHFSRTALTEKSKLDEDYLYMA>Y<ADIMAKSCHLEEGGENGEAEEEVEVSFEEK3755
RYR2VDPLHQLILLFSRTALTEKCKLEEDFLYMA>Y<ADIMAKSCHDEED-D--DGEEE-VKSFEEK3717
RYR3PDPLHQIILYFSRNALTERSKLEDDPLYTS>Y<SSMMAKSCQSGED-E--EEDEDKEKTFEEK3607
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.Y3725Dc.11173T>G Putative BenignSIFT:
Polyphen: