Paralogue Annotation for RYR1 residue 422

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 422
Reference Amino Acid: G - Glycine
Protein Domain:


Paralogue Variants mapped to RYR1 residue 422

No paralogue variants have been mapped to residue 422 for RYR1.



RYR1CQQEESQAARMIHSTNGLYNQFIKSLDSFS>G<KPRGSGPPAGTALPIEGVILSLQDLIIYFE452
RYR2SQHEESRTARVIRSTVFLFNRFIRGLDALS>K<KAKA----STVDLPIESVSLSLQDLIGYFH464
RYR3CQREESQAARIIRNTTALFSQFVSGN---->-<NRTA----APITLPIEEVLQTLQDLIAYFQ451
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.G422Rc.1264G>A Putative BenignSIFT:
Polyphen: