Paralogue Annotation for RYR1 residue 4244

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 4244
Reference Amino Acid: M - Methionine
Protein Domain:


Paralogue Variants mapped to RYR1 residue 4244

No paralogue variants have been mapped to residue 4244 for RYR1.



RYR1RQFIFDVVNEGGEAEKMELFVSFCEDTIFE>M<QIAAQISEPEGEPETDEDEGAGAAEAGAEG4274
RYR2RQFIFDVVNEGGEKEKMELFVNFCEDTIFE>M<QLAAQISESDLNERSANKEESEK-----ER4225
RYR3RQFIFDVVNEGGEQEKMELFVNFCEDTIFE>M<QLASQISESDSADRPEEEEEDEDSSYVLEI4126
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.M4244Tc.12731T>C Putative BenignSIFT:
Polyphen: