Paralogue Annotation for RYR1 residue 425

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 425
Reference Amino Acid: R - Arginine
Protein Domain:

Paralogue Variants mapped to RYR1 residue 425

No paralogue variants have been mapped to residue 425 for RYR1.

RYR1	EESQAARMIHSTNGLYNQFIKSLDSFSGKP>R<GSGPPAGTALPIEGVILSLQDLIIYFEPPS	455
RYR2	EESRTARVIRSTVFLFNRFIRGLDALSKKA>K<A----STVDLPIESVSLSLQDLIGYFHPPD	467
RYR3	EESQAARIIRNTTALFSQFVSGN-----NR>T<A----APITLPIEEVLQTLQDLIAYFQPPE	454
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See full Alignment of Paralogues

Known Variants in RYR1

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.R425W	c.1273C>T	Putative Benign			SIFT: Polyphen: