Paralogue Annotation for RYR1 residue 433

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 433
Reference Amino Acid: T - Threonine
Protein Domain:

Paralogue Variants mapped to RYR1 residue 433

No paralogue variants have been mapped to residue 433 for RYR1.

RYR1	IHSTNGLYNQFIKSLDSFSGKPRGSGPPAG>T<ALPIEGVILSLQDLIIYFEPPSEDLQHEEK	463
RYR2	IRSTVFLFNRFIRGLDALSKKAKA----ST>V<DLPIESVSLSLQDLIGYFHPPDEHLEHEDK	475
RYR3	IRNTTALFSQFVSGN-----NRTA----AP>I<TLPIEEVLQTLQDLIAYFQPPEEEMRHEDK	462
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See full Alignment of Paralogues

Known Variants in RYR1

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.T433M	c.1298C>T	Putative Benign			SIFT: Polyphen: