Paralogue Annotation for RYR1 residue 436

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 436
Reference Amino Acid: P - Proline
Protein Domain:

Paralogue Variants mapped to RYR1 residue 436

No paralogue variants have been mapped to residue 436 for RYR1.

RYR1	TNGLYNQFIKSLDSFSGKPRGSGPPAGTAL>P<IEGVILSLQDLIIYFEPPSEDLQHEEKQSK	466
RYR2	TVFLFNRFIRGLDALSKKAKA----STVDL>P<IESVSLSLQDLIGYFHPPDEHLEHEDKQNR	478
RYR3	TTALFSQFVSGN-----NRTA----APITL>P<IEEVLQTLQDLIAYFQPPEEEMRHEDKQNK	465
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See full Alignment of Paralogues

Known Variants in RYR1

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.P436R	c.1307C>G	Putative Benign			SIFT: Polyphen: