Paralogue Annotation for RYR1 residue 4403

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 4403
Reference Amino Acid: A - Alanine
Protein Domain:


Paralogue Variants mapped to RYR1 residue 4403

No paralogue variants have been mapped to residue 4403 for RYR1.



RYR1KVTVTELLAGMPDPTSDEVHGEQPAGPGGD>A<DGEGASEGAGDAAEGAGDEEEAVHEAGPGG4433
RYR2KIKVAELLANMPDPTQDEVRGDGEEGERKP>-<LEAALPSEDLTDLKELTEESDLLSD-----4378
RYR3NIRVTKILGDMPDPTQFGIHDDTMEAERAE>V<MEPGITTELVHFIKGEKGDTDIMSD-----4280
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.A4403Tc.13207G>A Putative BenignSIFT: tolerated
Polyphen: