Paralogue Annotation for RYR1 residue 4422

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 4422
Reference Amino Acid: E - Glutamate
Protein Domain:


Paralogue Variants mapped to RYR1 residue 4422

No paralogue variants have been mapped to residue 4422 for RYR1.



RYR1HGEQPAGPGGDADGEGASEGAGDAAEGAGD>E<EEAVHEAGPGGADGAVAVTDGGPFRPEGAG4452
RYR2RGDGEEGERKP-LEAALPSEDLTDLKELTE>E<SDLLSD-----IFGLDLKREGGQYKLIPHN4397
RYR3HDDTMEAERAEVMEPGITTELVHFIKGEKG>D<TDIMSD-----LFGLHPKKEGS-LKHGPEV4298
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.E4422Dc.13266G>C Putative BenignSIFT:
Polyphen: