Paralogue Annotation for RYR1 residue 4424

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 4424
Reference Amino Acid: E - Glutamate
Protein Domain:


Paralogue Variants mapped to RYR1 residue 4424

No paralogue variants have been mapped to residue 4424 for RYR1.



RYR1EQPAGPGGDADGEGASEGAGDAAEGAGDEE>E<AVHEAGPGGADGAVAVTDGGPFRPEGAGGL4454
RYR2DGEEGERKP-LEAALPSEDLTDLKELTEES>D<LLSD-----IFGLDLKREGGQYKLIPHNPN4399
RYR3DTMEAERAEVMEPGITTELVHFIKGEKGDT>D<IMSD-----LFGLHPKKEGS-LKHGPEVGL4300
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.Glu4424Alac.13271A>C UnknownSIFT:
Polyphen: