Paralogue Annotation for RYR1 residue 4425

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 4425
Reference Amino Acid: A - Alanine
Protein Domain:


Paralogue Variants mapped to RYR1 residue 4425

No paralogue variants have been mapped to residue 4425 for RYR1.



RYR1QPAGPGGDADGEGASEGAGDAAEGAGDEEE>A<VHEAGPGGADGAVAVTDGGPFRPEGAGGLG4455
RYR2GEEGERKP-LEAALPSEDLTDLKELTEESD>L<LSD-----IFGLDLKREGGQYKLIPHNPNA4400
RYR3TMEAERAEVMEPGITTELVHFIKGEKGDTD>I<MSD-----LFGLHPKKEGS-LKHGPEVGLG4301
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.A4425Ec.13274C>A Putative BenignSIFT:
Polyphen: