Paralogue Annotation for RYR1 residue 4487

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 4487
Reference Amino Acid: L - Leucine
Protein Domain:


Paralogue Variants mapped to RYR1 residue 4487

No paralogue variants have been mapped to residue 4487 for RYR1.



RYR1GDTTPAEPPTPEGSP-ILKRKLGVDGVEEE>L<PPEPEPEPEPELEPEKADAENGEKEEVPEP4517
RYR2SDLMSN-PVPMPE-V-QEKFQEQ--KA--->K<EEEKEEKEETKSEPEKAEGEDGEKEEKAKE4455
RYR3SEIIGKDEPPTLESTVQKKRKA---QA--->A<EMKAANEAEGKVESEKADMEDGEKEDKDKE4358
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.L4487Fc.13459C>T Putative BenignSIFT:
Polyphen: