Paralogue Annotation for RYR1 residue 4622

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 4622
Reference Amino Acid: G - Glycine
Protein Domain:


Paralogue Variants mapped to RYR1 residue 4622

No paralogue variants have been mapped to residue 4622 for RYR1.



RYR1MEGSAAGDVSGAGSGGSSGW-GLGAGEEAE>G<DEDENMVYYFLEESTGYMEPALRCLSLLHT4652
RYR2E------LPTRSSSENAK-VTSLDS----->S<SHRIIAVHYVLEESSGYMEPTLRILAILHT4580
RYR3E------DVANLWN-------SFND----->E<EEEEAMVFFVLQESTGYMAPTLRALAIIHT4485
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.G4622Ac.13865G>C Putative BenignSIFT:
Polyphen: