Paralogue Annotation for RYR1 residue 4642

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 4642
Reference Amino Acid: P - Proline
Protein Domain:


Paralogue Variants mapped to RYR1 residue 4642

No paralogue variants have been mapped to residue 4642 for RYR1.



RYR1-GLGAGEEAEGDEDENMVYYFLEESTGYME>P<ALRCLSLLHTLVAFLCIIGYNCLKVPLVIF4672
RYR2TSLDS-----SSHRIIAVHYVLEESSGYME>P<TLRILAILHTVISFFCIIGYYCLKVPLVIF4600
RYR3-SFND-----EEEEEAMVFFVLQESTGYMA>P<TLRALAIIHTIISLVCVVGYYCLKVPLVVF4505
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.P4642Ac.13924C>G Putative BenignSIFT:
Polyphen: