Paralogue Annotation for RYR1 residue 4660

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 4660
Reference Amino Acid: I - Isoleucine
Protein Domain:


Paralogue Variants mapped to RYR1 residue 4660

No paralogue variants have been mapped to residue 4660 for RYR1.



RYR1YYFLEESTGYMEPALRCLSLLHTLVAFLCI>I<GYNCLKVPLVIFKREKELARKLEFDGLYIT4690
RYR2HYVLEESSGYMEPTLRILAILHTVISFFCI>I<GYYCLKVPLVIFKREKEVARKLEFDGLYIT4618
RYR3FFVLQESTGYMAPTLRALAIIHTIISLVCV>V<GYYCLKVPLVVFKREKEIARKLEFDGLYIT4523
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.I4660Fc.13978A>T Putative BenignSIFT:
Polyphen: