Paralogue Annotation for RYR1 residue 774

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 774
Reference Amino Acid: G - Glycine
Protein Domain:

Paralogue Variants mapped to RYR1 residue 774

No paralogue variants have been mapped to residue 774 for RYR1.

RYR1	SCCLDLSVPSISFRINGCPVQGVFESFNLD>G<LFFPVVSFSAGVKVRFLLGGRHGEFKFLPP	804
RYR2	SCCLDLSAPSISFRINGQPVQGMFENFNID>G<LFFPVVSFSAGIKVRFLLGGRHGEFKFLPP	816
RYR3	SCCLDLGVPSISFRINGQPVQGMFENFNTD>G<LFFPVMSFSAGVKVRFLMGGRHGEFKFLPP	803
cons	> <

See full Alignment of Paralogues

Known Variants in RYR1

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.G774R	c.2320G>A	Putative Benign		rs147918857	SIFT: Polyphen: probably damaging