Paralogue Annotation for RYR1 residue 841

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 841
Reference Amino Acid: P - Proline
Protein Domain:

Paralogue Variants mapped to RYR1 residue 841

No paralogue variants have been mapped to residue 841 for RYR1.

RYR1	HEAVLPRERLHLEPIKEYRREGPRGPHLVG>P<SRCLSHTDFVPCPVDTVQIVLPPHLERIRE	871
RYR2	YEAVLPKEKLKVEHSREYKQERTYTRDLLG>P<TVSLTQAAFTPIPVDTSQIVLPPHLERIRE	883
RYR3	YEALLPKEKMRLEPVKEYKRDADGIRDLLG>T<TQFLSQASFIPCPVDTSQVILPPHLEKIRD	870
cons	> <

See full Alignment of Paralogues

Known Variants in RYR1

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.P841L	c.2522C>T	Putative Benign		rs368051427	SIFT: deleterious Polyphen: probably damaging