Paralogue Annotation for RYR1 residue 846

Residue details

Gene: RYR1
Reference Sequences: Ensembl variant: ENST00000359596 / ENSP00000352608
Amino Acid Position: 846
Reference Amino Acid: S - Serine
Protein Domain:

Paralogue Variants mapped to RYR1 residue 846

No paralogue variants have been mapped to residue 846 for RYR1.

RYR1	PRERLHLEPIKEYRREGPRGPHLVGPSRCL>S<HTDFVPCPVDTVQIVLPPHLERIREKLAEN	876
RYR2	PKEKLKVEHSREYKQERTYTRDLLGPTVSL>T<QAAFTPIPVDTSQIVLPPHLERIREKLAEN	888
RYR3	PKEKMRLEPVKEYKRDADGIRDLLGTTQFL>S<QASFIPCPVDTSQVILPPHLEKIRDRLAEN	875
cons	> <

See full Alignment of Paralogues

Known Variants in RYR1

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.S846L	c.2537C>T	Putative Benign		rs193922775	SIFT: Polyphen: possibly damaging