Paralogue Annotation for RYR2 residue 1166

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 1166
Reference Amino Acid: V - Valine
Protein Domain: Cytoplasmic region


Paralogue Variants mapped to RYR2 residue 1166

No paralogue variants have been mapped to residue 1166 for RYR2.



RYR2AFDGFKAQRWHQGNEHYGRSWQAGDVVGCM>V<DMNEHTMMFTLNGEILLDDSGSELAFKDFD1196
RYR1VFNGHRGQRWHLGSEPFGRPWQPGDVVGCM>I<DLTENTIIFTLNGEVLMSDSGSETAFREIE1182
RYR3VFEGNRGQRWHQGSGYFGRTWQPGDVVGCM>I<NLDDASMIFTLNGELLITNKGSELAFADYE1182
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.Val1166Ilec.3496G>A UnknownSIFT:
Polyphen: