Paralogue Annotation for RYR2 residue 1261

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 1261
Reference Amino Acid: V - Valine
Protein Domain: Cytoplasmic region


Paralogue Variants mapped to RYR2 residue 1261

No paralogue variants have been mapped to residue 1261 for RYR2.



RYR2GLQEGYEPFAVNTNRDITMWLSKRLPQFLQ>V<PSNHEHIEVTRIDGTIDSSPCLKVTQKSFG1291
RYR1GLQEGFEPFAINMQRPVTTWFSKGLPQFEP>V<PLEHPHYEVSRVDGTVDTPPCLRLTHRTWG1277
RYR3GLQEGFEPFAVNMNRDVAMWFSKRLPTFVN>V<PKDHPHIEVMRIDGTMDSPPCLKVTHKTFG1277
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.V1261Fc.3781G>T Putative BenignSIFT:
Polyphen: