Paralogue Annotation for RYR2 residue 1277

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 1277
Reference Amino Acid: I - Isoleucine
Protein Domain: Cytoplasmic region


Paralogue Variants mapped to RYR2 residue 1277

No paralogue variants have been mapped to residue 1277 for RYR2.



RYR2ITMWLSKRLPQFLQVPSNHEHIEVTRIDGT>I<DSSPCLKVTQKSFGSQNSNTDIMFYRLSMP1307
RYR1VTTWFSKGLPQFEPVPLEHPHYEVSRVDGT>V<DTPPCLRLTHRTWGSQNSLVEMLFLRLSLP1293
RYR3VAMWFSKRLPTFVNVPKDHPHIEVMRIDGT>M<DSPPCLKVTHKTFGTQNSNADMIYCRLSMP1293
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.I1277Vc.3829A>G Putative BenignSIFT:
Polyphen: